GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| UCEC | cis | rs9815354 | 1 | rs9866092 | chr3:41895967 | ULK4 | chr3:41288091-42003660:- | 0.52 | 6.25 | 3.94E-9 | Diastolic blood pressure |
| UCEC | cis | rs9815354 | 1 | rs9866759 | chr3:41758418 | ULK4 | chr3:41288091-42003660:- | 0.51 | 6.28 | 3.36E-9 | Diastolic blood pressure |
| UCEC | cis | rs9815354 | 1 | rs9869207 | chr3:41878661 | ULK4 | chr3:41288091-42003660:- | 0.54 | 6.51 | 1.02E-9 | Diastolic blood pressure |
| UCEC | cis | rs9815354 | 1 | rs9869282 | chr3:41756064 | ULK4 | chr3:41288091-42003660:- | 0.52 | 6.34 | 2.55E-9 | Diastolic blood pressure |
| UCEC | cis | rs9815354 | 1 | rs9869440 | chr3:41763155 | ULK4 | chr3:41288091-42003660:- | 0.52 | 6.38 | 2.06E-9 | Diastolic blood pressure |
| UCEC | cis | rs10935120 | 1 | rs9869981 | chr3:134248801 | ANAPC13 | chr3:134196547-134204865:- | 0.4 | 4.61 | 8.54E-6 | Height |
| UCEC | cis | rs9815354 | 1 | rs9874513 | chr3:41909508 | ULK4 | chr3:41288091-42003660:- | 0.43 | 4.44 | 1.7E-5 | Diastolic blood pressure |
| UCEC | cis | rs9815354 | 1 | rs9874975 | chr3:41764300 | ULK4 | chr3:41288091-42003660:- | 0.51 | 6.22 | 4.48E-9 | Diastolic blood pressure |
| UCEC | cis | rs9815354 | 1 | rs9875107 | chr3:41822313 | ULK4 | chr3:41288091-42003660:- | 0.5 | 5.72 | 5.58E-8 | Diastolic blood pressure |
| UCEC | cis | rs10935120 | 1 | rs9876658 | chr3:134179453 | ANAPC13 | chr3:134196547-134204865:- | -0.4 | -4.62 | 8.13E-6 | Height |
| UCEC | cis | rs9815354 | 1 | rs9876960 | chr3:41985812 | ULK4 | chr3:41288091-42003660:- | -0.51 | -6.12 | 7.79E-9 | Diastolic blood pressure |
| UCEC | cis | rs9815354 | 1 | rs9882329 | chr3:41767154 | ULK4 | chr3:41288091-42003660:- | 0.51 | 6.2 | 5.18E-9 | Diastolic blood pressure |
| UCEC | cis | rs10935120 | 1 | rs9883753 | chr3:134247231 | ANAPC13 | chr3:134196547-134204865:- | 0.38 | 4.37 | 2.26E-5 | Height |
| UCEC | cis | rs10935120 | 1 | rs9884031 | chr3:134256500 | ANAPC13 | chr3:134196547-134204865:- | 0.4 | 4.62 | 8.08E-6 | Height |
| UCEC | cis | rs9894429 | 1 | rs9894429 | chr17:79596811 | TSPAN10 | chr17:79609349-79615778:+ | 0.62 | 7.56 | 3.56E-12 | Eye color traits |